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Department
of Biological and Chemical Sciences BIOL1151 - INTRODUCTORY GENETICS (4 credits)
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Department
of Biological and Chemical Sciences BIOL1151 - INTRODUCTORY GENETICS (4 credits)
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Co-ordinator: |
Dr. L.D. Waterman |
Pre-requisite: |
One of CAPE Biology Unit 1, BIOL0051 or an approved equivalent. |
Co-requisite: |
None |
Syllabus: |
The Nature of the Genetic Material:
Experimental evidence implicating the nucleic acids. DNA structure - experimental evidence
& theory. DNA conformation. DNA Replication and Assortment: Semi-conservative. Modes of replication. The replication fork in Escherichia coli. DNA polymerases. The cell cycle. Organisation of eukaryotic chromatin. Mitosis and meiosis. Mendelism. Linkage and Recombination. The Genetic Material as an Information Carrier: The Central Dogma. Colinearity. Transcription and translation in prokaryotes & eukaryotes. Gene expression/regulation [lac and/or trp operons in E. coli]. Population Genetics: Gene pools; Transmission of genes between generations; Hardy-Weinberg (2 and 3 alleles); Selection pressures; selection against a recessive allele; mutation and migration. |
Teaching: |
Two lectures, one tutorial and three hours of practical per week. |
Method of Examination: |
Theory examination (2 hour) - 50%; Mid-semester test -15%; Tutorial Assignments -10%; Practical reports - 25% |
Copyright © 1998
Last modified: 15 February 2008
